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Age differences in the prevalence and co‐morbidity of DSM‐IV major depressive episodes: results from the WHO World Mental Health Survey Initiative

Identifieur interne : 007346 ( Main/Exploration ); précédent : 007345; suivant : 007347

Age differences in the prevalence and co‐morbidity of DSM‐IV major depressive episodes: results from the WHO World Mental Health Survey Initiative

Auteurs : Ronald C. Kessler [États-Unis] ; Howard G. Birnbaum [États-Unis] ; Victoria Shahly [États-Unis] ; Evelyn Bromet [États-Unis] ; Irving Hwang [États-Unis] ; Katie A. Mclaughlin [États-Unis] ; Nancy Sampson [États-Unis] ; Laura Helena Andrade [Brésil] ; Giovanni De Girolamo [Italie] ; Koen Demyttenaere [Belgique] ; Josep Maria Haro [Espagne] ; Aimee N. Karam [Liban] ; Stanislav Kostyuchenko [Ukraine] ; Viviane Kovess [France] ; Carmen Lara [Mexique] ; Daphna Levinson [Israël] ; Herbert Matschinger [Allemagne] ; Yoshibumi Nakane [Japon] ; Mark Oakley Browne [Australie] ; Johan Ormel [Pays-Bas] ; Jose Posada-Villa [Colombie] ; Rajesh Sagar [Inde] ; Dan J. Stein [Afrique du Sud]

Source :

RBID : ISTEX:5AE7319259BC3431796E1A915295E52134A0A4BB

Descripteurs français

English descriptors

Abstract

Background: Although depression appears to decrease in late life, this could be due to misattribution of depressive symptoms to physical disorders that increase in late life. Methods: We investigated this issue by studying age differences in co‐morbidity of DSM‐IV major depressive episodes (MDE) with chronic physical conditions in the WHO World Mental Health (WMH) surveys, a series of community epidemiological surveys of respondents in 10 developed countries (n=52,485) and 8 developing countries (n=37,265). MDE and other mental disorders were assessed with the Composite International Diagnostic Interview (CIDI). Organic exclusion rules were not used to avoid inappropriate exclusion of cases with physical co‐morbidity. Physical conditions were assessed with a standard chronic conditions checklist. Results: Twelve‐month DSM‐IV/CIDI MDE was significantly less prevalent among respondents ages 65+ than younger respondents in developed but not developing countries. Prevalence of co‐morbid mental disorders generally either decreased or remained stable with age, while co‐morbidity of MDE with mental disorders generally increased with age. Prevalence of physical conditions, in comparison, generally increased with age, while co‐morbidity of MDE with physical conditions generally decreased with age. Depression treatment was lowest among the elderly in developed and developing countries. Conclusions: The weakening associations between MDE and physical conditions with increasing age argue against the suggestion that the low estimated prevalence of MDE among the elderly is due to increased confounding with physical disorders. Future study is needed to investigate processes that might lead to a decreasing impact of physical illness on depression among the elderly. Depression and Anxiety, 2010. © 2009 Wiley‐Liss, Inc.

Url:
DOI: 10.1002/da.20634


Affiliations:


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Le document en format XML

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<term>Organic exclusion rules</term>
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<term>Africa stress</term>
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<term>Cambridge university press</term>
<term>Cape town</term>
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<term>Ciber retics</term>
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<term>Conditional prevalence</term>
<term>Conditional prevalence estimate</term>
<term>Conditions checklist</term>
<term>Confidence interval</term>
<term>Contract grant number</term>
<term>Contract grant numbers</term>
<term>Contract grant sponsor</term>
<term>Contract grant sponsors</term>
<term>Contrast category</term>
<term>Depression treatment</term>
<term>Depressive</term>
<term>Depressive symptomatology</term>
<term>Depressive symptoms</term>
<term>Diagnostic hierarchy rules</term>
<term>Diagnostic interview</term>
<term>Dichotomous measure</term>
<term>Dichotomous predictor</term>
<term>Differences columns test</term>
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<term>Disorderd number</term>
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<term>Drug abuse</term>
<term>Elderly people</term>
<term>Emotional problems</term>
<term>Epidemiological studies</term>
<term>Esemed</term>
<term>European commission</term>
<term>Future study</term>
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<term>Good concordance</term>
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<term>Groups table</term>
<term>Health care policy</term>
<term>Health research council</term>
<term>Health study</term>
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<term>Health surveys</term>
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<term>Highest prevalence</term>
<term>Household residents</term>
<term>Household samples</term>
<term>Human services</term>
<term>Impairment</term>
<term>Investigacion sanitaria</term>
<term>Janssen cilag</term>
<term>Japan ministry</term>
<term>Kessler</term>
<term>Late life</term>
<term>Lebanese ministry</term>
<term>Lebanon</term>
<term>Lifetime episodes</term>
<term>Lifetime onset</term>
<term>Lilly company</term>
<term>Lilly company foundation</term>
<term>Linear regression results</term>
<term>Logistic</term>
<term>Logistic regression equation</term>
<term>Lung disease</term>
<term>Macarthur foundation</term>
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<term>Major depressive episodes</term>
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<term>Medical health care</term>
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<term>Mental health services administration</term>
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<term>National health interview survey</term>
<term>National institute</term>
<term>National insurance institute</term>
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<term>Oldest respondents</term>
<term>Onee twoe</term>
<term>Organic exclusion rules</term>
<term>Organic exclusions</term>
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<term>Pfizer foundation</term>
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<term>Psychol</term>
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<term>Specific phobia</term>
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<term>Statistical significance</term>
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<term>World bank</term>
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<front>
<div type="abstract" xml:lang="en">Background: Although depression appears to decrease in late life, this could be due to misattribution of depressive symptoms to physical disorders that increase in late life. Methods: We investigated this issue by studying age differences in co‐morbidity of DSM‐IV major depressive episodes (MDE) with chronic physical conditions in the WHO World Mental Health (WMH) surveys, a series of community epidemiological surveys of respondents in 10 developed countries (n=52,485) and 8 developing countries (n=37,265). MDE and other mental disorders were assessed with the Composite International Diagnostic Interview (CIDI). Organic exclusion rules were not used to avoid inappropriate exclusion of cases with physical co‐morbidity. Physical conditions were assessed with a standard chronic conditions checklist. Results: Twelve‐month DSM‐IV/CIDI MDE was significantly less prevalent among respondents ages 65+ than younger respondents in developed but not developing countries. Prevalence of co‐morbid mental disorders generally either decreased or remained stable with age, while co‐morbidity of MDE with mental disorders generally increased with age. Prevalence of physical conditions, in comparison, generally increased with age, while co‐morbidity of MDE with physical conditions generally decreased with age. Depression treatment was lowest among the elderly in developed and developing countries. Conclusions: The weakening associations between MDE and physical conditions with increasing age argue against the suggestion that the low estimated prevalence of MDE among the elderly is due to increased confounding with physical disorders. Future study is needed to investigate processes that might lead to a decreasing impact of physical illness on depression among the elderly. Depression and Anxiety, 2010. © 2009 Wiley‐Liss, Inc.</div>
</front>
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